Precipitation of Inorganic Salts in Mitochondrial Matrix

Arsenic, inorganic and soluble salts

Inhibition of mitochondrial-matrix inorganic pyrophosphatase by physiological [Ca2+], and its role in the hormonal regulation of mitochondrial matrix volume.

1. The pyrophosphatase activity in cytosolic and mitochondrial fractions of rat liver was 1.7 and 0.26 units/mg of protein respectively when assayed at 37 degrees C in the presence of physiological [Mg2+] (0.3 mM). 2. Approx. 80% of the mitochondrial pyrophosphatase was inaccessible to extramitochondrial PPi, of which 40% represented soluble matrix enzyme (0.38 unit/mg of matrix protein). 3. Ca...

Precipitation Reaction of SDS and Potassium Salts in Flocculation of a Micronized Megestrol Acetate Suspension

In this work attempts were made to evaluate K+-SDS and hydrocolloid polymer-SDS interactions in flocculation of megestrol acetate dispersions to enhancetheir stability as a part of suspension formulation. Different dispersions of micronized megestrol acetate and SDS were prepared. KCl and KH2PO4 and their corresponding sodium salts were added to the dispersions and the preparations were evaluat...

Precipitation Reaction of SDS and Potassium Salts in Flocculation of a Micronized Megestrol Acetate Suspension

In this work attempts were made to evaluate K+-SDS and hydrocolloid polymer-SDS interactions in flocculation of megestrol acetate dispersions to enhancetheir stability as a part of suspension formulation. Different dispersions of micronized megestrol acetate and SDS were prepared. KCl and KH2PO4 and their corresponding sodium salts were added to the dispersions and the preparations were evaluat...

Precipitation of Polyelectrolytes in the Presence of Multivalent Salts

We present a theory of the complexation of polyanions by divalent cations. The formation of both mono-and dicomplexes is possible. Monocomplexation locally inverts the charge of the polyelectrolyte and transforms it into a polyampholyte. The formation of a dicomplex creates a bridge between charged monomers. The complexation constants for mono and dicomplexation strongly decrease at high ionic ...